ACTC1 Antikörper (N-Term)

Produktnummer ABIN5539979

Dieser Maus Monoklonal Antikörper erkennt spezifisch ACTC1 in WB, IHC (fro) und EIA. Er zeigt eine Reaktivität gegenüber Human, Ratte, Zebrafisch (Danio rerio), Kaninchen und Schwein.

Kurzübersicht für ACTC1 Antikörper (N-Term) (ABIN5539979)

Target: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Reaktivität: Human, Ratte, Zebrafisch (Danio rerio), Kaninchen, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ACTC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: 22D3

Produktdetails anti-ACTC1 Antikörper

Bindungsspezifität: N-Term

Sequenz: Ac-DDEETTALVC -COOH

Spezifität: This 22D3 Monoclonal antibody is highly specific for Alpha-Cardiac Actin, and does not cross react with other Actin isoforms.

Aufreinigung: Purified

Immunogen: Peptide comprising the N-terminal nonapeptide of alpha-Cardiac Actin with an acetylated N-terminus coupled to keyhole limpet hemocyanin through the cysteine residue.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Flow Cytometry. Immunoblotting. Immunofluorescence. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin-Embedded Sections. Recommended Dilutions : 1/100-1/1000 for Immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent and 1/1000-1/5000 for immunoblotting applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freeze-thaw cycles. Shelf life: One year from despatch.

Details zu ACTC1

Target: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Andere Bezeichnung: alpha 1 cardiac muscle actin,actc1

Hintergrund: Among the six actin isoforms described in mammals, two are found in virtually all cells (β- and γ-cytoplasmic), two are detected in smooth muscle cells (α- and γ-smooth muscle) and two are present in striated muscles, one predominantly in skeletal (α-skeletal) and one in cardiac (α-cardiac) muscle cells. These actin isoforms differ slightly in their N-terminus, but the sequence of each of these actins is highly conserved in higher vertebrates. Cardiac α-actin, which is the main actin isoform in the adult heart, has also been shown to be the predominant form in early muscle development. In later development the expression of α-cardiac actin is down regulated and α-skeletal actin becomes the dominant isoform in the adult skeletal muscle.

Pathways: Myometrial Relaxation and Contraction